Fracture related infections (FRI’s) occur when bacteria or other pathogens infect bones, tissues or fixation materials after a fracture took place. In 2020, an updated definition for FRI was introduced, helping to better differentiate these infections from other joint related infections. This master thesis’ research focused on two main goals: 1) gathering and summarizing information about FRI and 2) describing the current characteristics and results for 41 FRI patients who were treated at the University Hospital in Ghent. This master thesis showed that most patients were male, with an average age of 51 years old, and that the infections often occurred acutely after initial surgery for the fracture (meaning within 3 weeks after surgery). The most commonly reported pathogen was Staphylococcus aureus and generally similar bacteria were observed in comparison to other FRI literature. After an average follow-up period of 17 months, most patients were successfully treated at the University Hospital in Ghent, but treatment failure was higher than in other studies. This can be attributed to the fact that the patient population for this master thesis consisted of only complex cases of FRI, whereas most literature focuses on broader FRI populations that are less challenging to treat.