The Belgian Medical Regulation Manual (BMRM) is the manual used by the operators of the emergency dispatch centres. When someone is in medical distress, they can call the European emergency number 112. A call to 112 is answered by an operator of an emergency dispatch centre. The operator assesses the person's condition and tries to estimate the urgency of the situation. Depending on the situation, the operator will use a specific protocol of the BMRM, matching the medical complaint. The protocols of the BMRM make use of a flowchart system. In this way, an operator will systematically go through an emergency situation and ask targeted questions. The protocols lead to the selection of a particular level of urgency and they enable the operator to give appropriate instructions that can benefit the person’s situation. The instructions passed along to the caller can be seen as first-aid instructions. The operator will thus guide an individual in administering first aid while waiting for professional medical assistance to arrive on the scene. The urgency levels from which an operator can choose are medical emergency group 1 and 2 (MUG1/2), paramedical intervention team 3 and 4 (PIT3/4), ambulance 5 (ZW5), and finally three general practitioner (GP) levels (HA6/HA7/HA8). These urgency levels are linked to a response time and a certain composition of the emergency response team. A MUG and a PIT move out from the hospital itself. A MUG consists of an emergency physician and an emergency nurse. A MUG cannot transport people and is therefore always assisted by an ambulance. A PIT consists of an emergency nurse and an ambulance technician, while an ambulance consists of two ambulance technicians. Finally, the GP levels concern an out-of-hours GP or the habitual GP of the caller. This master's thesis attempts to evaluate the test performance of the BMRM by using 60 fictitious cases. A reference standard was established to see whether the operators of the emergency dispatch centres of West and East Flanders make the same choices as an emergency physician/emergency nurse. The agreement concerning the choice of urgency level, protocol and pre-arrival instructions will be examined. In addition, trends regarding certain choices will be researched and difficulties within the BMRM will be defined. Lastly, a comparison with our northern neighbours will be performed. An operator of a Dutch ambulance dispatch centre assessed the same 60 cases in terms of urgency level, protocol, and instructions. This can help to compare if situations in Belgium and the Netherlands are assessed in a similar manner. The social importance of this study lies in the widespread use of the European emergency number 112. It is important that a victim for whom a call is made receives adequate medical treatment. If the BMRM leads to an overestimation of situations, medical resources and emergency workers would be deployed unnecessarily. This would mean that resources, at that time, are no longer available for another person. If the BMRM leads to an underestimation of emergency situations, it could potentially be dangerous for people in need of urgent care. They could receive inadequate care or they could be treated too late, which could permit their condition to deteriorate. It should be noted that the emergency dispatch centres are the first link in emergency medical services. If a problem is present in this link of the chain, it has repercussions on the rest of the healthcare system.